identification ability

By Targets:	Biochemical Assay Reagents (1) Phosphodiesterase (PDE) (1)
By Research Areas:	Neurological Disease (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-153093

MK-8189	Phosphodiesterase (PDE)	Neurological Disease
MK-8189 is a potent, orally active and selective PDE10A inhibitor with a K_i value of 29 pM. MK-8189 can be used in research of schizophrenia .

HY-W250177

Tridodecylmethylammonium chloride	Biochemical Assay Reagents	Others
Tridodexylmethylammonium chloride, also known as TDMAC, is a cationic surfactant commonly used in various industrial and research applications. It belongs to the family of quaternary ammonium compounds and has a positively charged head and a hydrophobic tail, which allows it to be used as a detergent, emulsifier and antimicrobial. Known for its ability to disrupt cell membranes, TDMAC is frequently used in microbiology for the selective isolation and identification of bacteria.

Cat. No.	Product Name

HY-L063

Chemical Probe Library	274 compounds
Chemical probes are simply reagents with high potency, selectivity and cell-permeability which play important roles in both fundamental and applied biological research. In their most common application, chemical probes can establish the tractability of a specific target. They are used to interrogate the relationship between a target and its phenotype (biological tractability) as well as an ability to modulate that phenotype using a small molecule. Otherwise, chemical probes also have had a major impact in enabling and accelerating discoveries along the path to pioneer medicines. They have helped to improve the understanding of targets and pathways and have created opportunities for proprietary drug discovery efforts to an extent that would not have been possible otherwise. MCE provides a unique collection of 274 chemical probes with high potency (at least 100 nM potency), selectivity (at least 10-fold selectivity against any other target) and cell-permeability (at least 10 μM potency). MCE Chemical probe library is a useful tool for target identification and mechanism research.

Chemical Probe Library

274 compounds

Chemical probes are simply reagents with high potency, selectivity and cell-permeability which play important roles in both fundamental and applied biological research. In their most common application, chemical probes can establish the tractability of a specific target. They are used to interrogate the relationship between a target and its phenotype (biological tractability) as well as an ability to modulate that phenotype using a small molecule. Otherwise, chemical probes also have had a major impact in enabling and accelerating discoveries along the path to pioneer medicines. They have helped to improve the understanding of targets and pathways and have created opportunities for proprietary drug discovery efforts to an extent that would not have been possible otherwise.

MCE provides a unique collection of 274 chemical probes with high potency (at least 100 nM potency), selectivity (at least 10-fold selectivity against any other target) and cell-permeability (at least 10 μM potency). MCE Chemical probe library is a useful tool for target identification and mechanism research.

Cat. No.	Product Name	Type

HY-W250177

Tridodecylmethylammonium chloride	Biochemical Assay Reagents
Tridodexylmethylammonium chloride, also known as TDMAC, is a cationic surfactant commonly used in various industrial and research applications. It belongs to the family of quaternary ammonium compounds and has a positively charged head and a hydrophobic tail, which allows it to be used as a detergent, emulsifier and antimicrobial. Known for its ability to disrupt cell membranes, TDMAC is frequently used in microbiology for the selective isolation and identification of bacteria.

Tridodecylmethylammonium chloride

Biochemical Assay Reagents

Tridodexylmethylammonium chloride, also known as TDMAC, is a cationic surfactant commonly used in various industrial and research applications. It belongs to the family of quaternary ammonium compounds and has a positively charged head and a hydrophobic tail, which allows it to be used as a detergent, emulsifier and antimicrobial. Known for its ability to disrupt cell membranes, TDMAC is frequently used in microbiology for the selective isolation and identification of bacteria.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Screening Libraries

Biochemical Assay Reagents

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